- Exit-of-mitosis Mutants
- cdc14-ts
- cdc14-ts GAL-SIC1
- cdc14ts then GAL-SIC1
- cdc14-ts cdh1∆
- cdc14-ts sic1∆
- cdc14-ts GAL-CLN2
- net1-ts
- net1-ts in nocodazole
- net1∆ cdc20-ts
- tem1∆ net1-ts
- cdc15∆ net1-ts
- cdc15∆ net1-ts cdh1∆
- GAL-NET1
- GAL-CDC14
- GAL-NET1 GAL-CDC14
- cdc15-ts multicopy CDC14
- tem1-ts multicopy CDC14
- TAB6-1
- TAB6-1 cdc15∆
- TAB6-1 clb5∆ clb6∆
- TAB6-1 CLB1 clb2∆
cdc14-ts GAL-CLN2
debug: ,
test user =
test db =
Simulation:
Change of parameters: ksn2'=0.12, ksn2"=0, 20% Cdc14 activity (kppc1=kppf6=0.8, kaswi=0.4, kacdh"=0.16), MDT=150.
Arrest: Synthetically lethal, telophase arrest when Cdc14 activity is reduced.
Experiments:
Yuste-Rojas, M. and Cross, F.R. (2000). Mutations in CDC14 result in high sensitivity to cyclin gene dosage in Saccharomyces cerevisiae. Mol. Gen. Genet. 263:60-72.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Fig. 1, synthetically lethal at 30 C (a permissive temperature of cdc14-ts.
Comments:
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